Research Groups

Research Groups

Immunological Diagnostics

Assoc. Prof. Michael Dworzak, MD

We aim at developing and evaluating new diagnostic, prognostic and therapeutic approaches for paediatric leukaemias using high-end multi-colour flow cytometry.

Biology of Leukaemias


We are trying to understand why and how leukemia evolves and use our knowledge to improve treatment and advance cure of affected children.

Genetics of Leukaemias

Sabine Strehl, PhD

Tracking down the faulty genes that cause leukamia with the ultimate goal to establish predictive biomarkers for the optimisation of risk-adapted therapy.

Tumour Biology

Dr. Sabine Taschner-Mandl, PhD

We aim to establish, validate and apply new diagnostic and therapeutic tools to facilitate personalised treatment of children with malignant tumours.

Molecular Biology of Solid Tumours

Prof. Heinrich Kovar, PhD

To increase therapeutic efficacy while decreasing side effects, we have to specifically target the Achille`s heel of the disease.

Epigenome-based Precision Medicine

Eleni M. Tomazou, PhD

The aim of our group is to establish an epigenome-based precision medicine program for pediatric sarcomas.

Development of Cellular Therapeutics

Prof. Wolfgang Holter, MD

Our group focuses on the development of therapeutic strategies based on T cells modified with chimeric antigen receptors (CARs).

Clinical Cell Biology and FACS Core Unit

Assoc. Prof. René Geyeregger, PhD

With our engagement in flow cytometry and GMP-compliant work, we are a supportive interface between research and therapy.

Tumour Immunoediting

Dr. Eva Maria König

We study the role of NK cells in tumor immunoediting and aim to identify the molecular mechanisms of tumor immune evasion.

Molecular Microbiology

Prof. Thomas Lion, MD, PhD

Our group primarily focuses on the improvement of treatment outcomes, particularly in transplant recipients and patients with life-threatening infections, by developing and implementing new diagnostic technologies.

Studies & Statistics for Integrated Research and Projects

Prof. Ruth Ladenstein, MD, MBA, cPM

Multinational networking is fundamental for clinical research of malignant cancer in children and adolescents. Only controlled large-scale clinical trials allow improving complex treatment strategies, whilst smaller studies allow testing innovative drug medications to further improve survival rates. The clinical trail unit S2IRP undertakes all efforts to serve the complex tasks of clinical trial management.

LCH Biology

Caroline Hutter MD, PhD

The goal of our laboratory is to better understand the pathobiology of Langerhans Cell Histiocytosis (LCH) in order to develop new treatment approaches to the disease.

Innovative Cancer Models

Martin Distel, PhD

Our research focus is on the generation of pediatric cancer models in zebrafish to better understand tumor initiation and tumor progression on a cellular and molecular level. In addition, zebrafish disease models are applied in small compound screens to identify therapeutic compounds.

Integrative Analysis

Florian Halbritter, PhD

We combine "multi-omics" analysis with computational, statistical, and machine learning methods to dissect the molecular framework of pediatric cancers.

Officially starting at the CCRI in September 2018