Technical Assistant in the field of Genetics (m/f/d)
Immune Deficiency, Cancer Predispostion & Precision Oncology
To strengthen our international and multidisciplinary research team, we are looking for a driven and coordinated Technical Research Assistant (m/f/d) with a strong interest in genetics, immunology and pediatric cancer. The new team member will substantially contribute to the maintenance and optimization of our streamlined workflow for next generation sequencing (NGS)-based genetic analyses, the overall operation of the lab, and research documentation, as well as the establishment of a structured precision oncology program. They will also be involved in the development and implementation of novel assays, tools, and infrastructure, which include the migration of our current patient/genetic database to a new IT platform, and the systematic and safe exchange of data with international research institutions.
Kaan Boztug, a leading expert in research on immune deficiencies and bone marrow failure syndromes, and PI of an ERC Consolidator grant (“iDysChart”), acts as Scientific Director of the St. Anna Children’s Cancer Research Institute (https://science.ccri.at/research/research-areas/immunology/immune-deficiency-cancer-predisposition-precision-oncology/). The group works at the interface of inborn immune disorders and inherited predisposition to childhood tumors, aiming at understanding the fundamental mechanisms of immune surveillance relevant to pediatric oncology and immunotherapy approaches. We apply state-of-the-art genetic and genomic technologies like next generation sequencing, and a wide range of cellular and molecular techniques to elucidate the molecular architecture of the immune system and its interplay with childhood malignancy.
- Genetics/Genomics: PCR (incl. primer design), conventional (Sanger) sequencing, NGS-based methods (e.g. exome sequencing, genome sequencing, ATAC-Seq, RNAseq)
- Interpretation, reporting and documentation of genetic findings to external collaborators and into a local database
- Cell Culture: Isolation and culturing of peripheral blood mononuclear cells (PBMCs) and nucleic acid isolation from human samples
- Contribution to general lab management as part of the weekly, bi-weekly, or monthly rotating lab duties schedules (e.g. ordering, preparation of general reagents, sample processing, and others) as well as training of new lab members
- University or University of Applied Sciences degree in Life Sciences or a related field
- Proven experience in genetics, and standard molecular techniques (e.g. PCR, DNA/RNA extraction); previous experience in NGS-based methods is of advantage
- BMA diploma would be a plus
- Excellent communication skills (oral and written) in English and German
- Ability to work independently, learn quickly, and pay attention to detail
- A meaningful, inspiring, and international environment
- An outstanding working atmosphere in a strong team with excellent research and development opportunities
- Access to state-of-the-art infrastructure
- The possibility to become an expert in the growing field of next generation sequencing-based methods
- The option to set up and advance a quality management system partially independent and together with scientists from other research groups
- Flexible working hours, discounted lunch in our canteen and other great benefits
- Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
- A fair and attractive salary package starting at € 2.500,-- gross (14x per year) on full-time basis with a view to increase based on your qualification and experience
Who we are
The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).
The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to race, color, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.
Please submit your application via email to Kaan Boztug, email@example.com. Applications should at least contain your Curriculum Vitae and your motivation letter. The deadline for the application is 18th of October 2020.