Master Thesis – Molecular Microbiology

Master Thesis – Molecular Microbiology

We are looking for a highly motivated student interested in carrying out a Master Thesis in our multidisciplinary team in the Division of Molecular Microbiology. The aim of the project is to investigate the mechanism of adenovirus persistence and reactivation in oncological patients undergoing allogeneic stem cell transplantation. Due to the lack of a functional immune response in these patients, virus infections can be life-threatening. In our team, major advances have been made towards understanding the relevance of intestinal adenovirus infections in the immunosuppressed host and our data have contributed to improved diagnostic and therapeutic approaches in this setting.

We exploit a spectrum of techniques including the cultivation and infection of mammalian cells and intestinal organoids, molecular biological approaches to investigating viral replication and cytokine release, immunohistochemistry and in-situ hybridization for detection of the virus in histologic specimens.

The position is available by April, 2019, for the duration of 12 months.

If you are interested in this topic, please send an application including your CV, letter of motivation and contact details of a reference person to Karin Kosulin, email: hr@ccri.at