PhD Thesis “Establishing a Ewing Sarcoma model in zebrafish”.
PhD Thesis Opportunity
The “Innovative Cancer Models” group at the Children’s Cancer Research Institute (CCRI) in Vienna is looking for a highly motivated student interested in carrying out a PhD Thesis project on “Establishing a Ewing Sarcoma model in zebrafish”.
Ewing Sarcoma is a malignant bone tumor of children and young adults with high metastatic potential. Unfortunately, no adequate animal models are currently available to better understand the disease.
The aim of this project is to establish a Ewing Sarcoma model in zebrafish to investigate the etiology of the disease and the molecular mechanisms driving tumor formation. Ultimately, the model should be applied in a drug screen, to identify potential therapeutic compounds.
This project will be carried out in close collaboration with the “Molecular Biology of solid tumors” group and the head of this group, Prof. Heinrich Kovar will be a co-supervisor.
The CCRI is equipped with a state-of-the-art zebrafish facility, cutting-edge microscopes and an automated zebrafish drug screening platform (Danio4Can).
The position is available immediately and should ideally be filled by March 2018.
Successful applicants will be offered a salary according to the Austrian Science Fund standards (http://www.fwf.ac.at/de/forschungsfoerderung/personalkostensaetze/).
If you are interested in this topic, please send an application including your CV, a letter of motivation and the name of 2 referees to Martin Distel, email: hr(at)ccri.at by December 22nd.
The CCRI is situated in the center of Vienna, one of Europe’s most important places for medical research and life sciences and cited as the most livable city in the world. It hosts nearly 100 investigators working in the fields of pediatric leukemia, solid tumors, immunology and stem cell transplantation. Tightly associated with St. Anna Children´s hospital, the biggest center for pediatric hematology and oncology in Austria and one of the leading treatment centers for children with cancer in Europe, the CCRI performs basic, translational and clinical research.